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CAS: 52-86-8
分子式: C21H23ClFNO2
分子量: 375.88
中文名称: 
氟哌啶醇
卤吡醇
氟哌丁苯
氟哌醇
英文名称: 
pernox
gamma-(4-(p-chlorophenyl)-4-hydroxypiperidino)-p-fluorobutyrophenone
haldol
halol
halopal
haloperidol
halopoidol
keselan
lealgin compositum
linton
mcn-jr-1625
peluces
gamma-(4-(p-chlorophenyl)-4-hydroxypiperidino)-p-fluorbutyrophenone
r 1625
serenace
serenase
serenelfi
sernas
sernel
ulcolind
uliolind
vesalium
4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-4'-(4-flurophenyl)-1-butanone
Seranace
aldo
1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine
1-butanone, 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)
4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanon
4'-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidinyl)butyrophenone
4'-fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone
4'-fluoro-4-(4-hydroxy-4-p-chlorophenylpiperidino)butyrophenone
4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-buta none
4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone
4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone
4-(4-hydroxy-4'-chloro-4-phenylpiperidino)-4'-fluorbutyrophenone
4-(4-hydroxy-4'-chloro-4-phenylpiperidino)-4'-fluorobutyrophenone
4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4'-fluoro-butyrophenon
aloperidin
aloperidolo
aloperidon
brotopon
4'-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-butyrophenon
dozic
einalon s
eukystol
fortunan
galoperidol
性质描述: 白色或类白色结晶性粉末。熔点148-149.4℃。溶于氯仿、甲醇、丙酮、苯、稀酸,在水中的溶解度1.4mg/100ml,微溶于乙醚。无臭、无味。
生产方法: 由4-对氯苯-4-羟基哌(见09670)与γ-氯代对氟苯丁酮缩合而得。中间体γ-氯代氟苯丁酮是由氟苯、γ-丁内酯、氯化亚砜为原料制得(见09060)。
用途: 该品为丁酰苯类抗精神病药中最常用的药物,且列入《国家基本药物目录》。抗精神病药物,过去称为强安定剂,主要用于控制精神分裂证及其他具有幻觉、妄想、兴奋、冲动等症关的疾病。氟哌啶醇主要用于抗急、慢性精神分裂证的躁狂和幻觉,对控制兴奋躁动效果显著,但对精神分裂症的抑郁和淡漠无效。大鼠口服LD50为165mg/kg。
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