CAS 53-06-5; 可的松; 11-dehydro-17-hydroxycorticosterone

CAS:

53-06-5

分子式:

C21H28O5

分子量:

360.45

中文名称:

可的松

肾上腺皮质激素

17-羟-11脱氢皮质(甾)酮

17-羟-11-脱皮质(甾)酮

11-去氢-17-羟基皮质酮

英文名称:

cortivite

cortison

17,21-Dihydroxy-4-pregnene-3,11,20-trione

wintersteiner's compound f

reichstein's substance fa

20-trione, 17,21-dihydroxy-pregn-4-ene-11

pregn-4-en-17alpha,21-diol-3,11,20-trione

kendall's compound e

delta (sup 4)-pregnene-17alpha,21-diol-3,11,20-trione

cortone

11-dehydro-17-hydroxycorticosterone

cortisone

cortisate

compound e

adrenalex

4-pregnene-17alpha,21-diol-3,11,20-trione

17alpha,21-dihydroxypregn-4-ene-3,11,20-trione

17alpha,21-dihydroxy-4-pregnene-3,11,20-trione

17-hydroxy-11-dehydrocorticosterone

17-alpha-hydroxy-11-dehydrocorticosterone

性质描述:

白色结晶性粉末。熔点220-224℃（部分分解）。溶于乙醇、丙酮和冷甲醇，极少溶于醚、苯和氯仿，微溶于水（28mg/ml）。肾上腺皮质激素是哺乳动物的肾上腺产生的激素，约有30种肾上腺皮质激素已被分离和鉴定，其中约10种有生物活性。缺乏这些激素可引起无力、糖和蛋白质代谢失常以及电解质平衡失调等，最后导致死亡。