CAS 6055-19-2; 环磷酰胺; 2h-1,3,2-oxazaphosphorine, tetrahydro-2-(bis(2-chloroethyl)amino)-, 2-oxide, mo

CAS:

6055-19-2

分子式:

C7H17Cl2N2O3P

分子量:

279.10

沸点:

110℃

熔点:

49-53℃

中文名称:

环磷酰胺

安道生

环磷氮芥

癌得星

N,N-双(β-氯乙基)-N',O-三次甲基磷二酰胺酸酯-水化合物

英文名称:

endoxan monohydrate

2H-1,3,2-Oxazaphosphorin-2-amine,N,N-bis[2-chloroethyl]tetrahydro-,2-oxide,monohydrate

N,N-Bis-2-chloroethyl-N',O-propylene phosphoric ester diamide monohydrate

cyclophosphamide,monohydrate

Procy-tox

N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphos-phorin-2-amine 2-oxide

n,n-di(2-chloroethyl)amino-n,o-propylene phosphoric acid ester diamide monohy

n,n-bis(beta-cloraethyl) n'-o-propylenphosphorildiamid monohydratum

n,n-bis(beta-chloroethyl)-n',o-trimethylenephosphoric acid ester diamide mono

n,n-bis(beta-chloroethyl)-n',o-propylenephosphoric acid ester amide monohydra

n,n-bis(2-chloroethyl)tetrahydro-2h-1,3,2-oxaphosphorin-2-amine, 2-oxide mono

2h-1,3,2-oxazaphosphorine, tetrahydro-2-(bis(2-chloroethyl)amino)-, 2-oxide, mo

cyclophosphamide monohydrate

cyclophosphamide hydrate

cyclic n',o-propylene ester of n,n-bis(2-chloroethyl)phosphorodiamidic acid m

bis(2-chloroethyl)phosphoramide cyclic propanolamide ester monohydrate

2-(di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane-2-oxide monohydra

2-(bis(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphocyclohexane 2-oxide monohydr

1-bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridine monohydrate

-2 monohydrate

(bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-o xide

性质描述:

白色结晶或结晶性粉末。熔点41-45℃。水中溶解度40g/L，微溶于醇、苯、乙二醇、四氯化碳、二氧六圜，几乎不溶于乙醚及丙酮。失去结晶水即液化，水溶液不稳定。无臭、味微苦。

生产方法:

由二乙醇胺经氯化、缩合、环合而得。

用途:

抗肿瘤药。用于恶性淋巴瘤效果好，对急性淋巴白血病也具一定疗效，其他对慢性淋巴细胞白血病、乳癌、卵巢癌、睾丸癌、多发性骨髓瘤、神经母细胞瘤、头颈部癌和结肠癌等也有效。本品尚有免疫抑制作用。用于肾病缩合症和类风湿性关节炎等。该品毒性，对老鼠口服LD50为35094mg/kg。

6055-19-2 供应商：