CAS 61-12-1; 辛可卡因; 2-butoxy-n-(2-(diethylamino)ethyl)-cinchoninamid monohydrochloride

CAS:

61-12-1

分子式:

C20H30ClN3O2

分子量:

379.92

熔点:

99-101℃

中文名称:

辛可卡因

狄布卡因

奴百卡因

拍卡因

沙夫卡因

狄布卡因盐酸盐

地布卡因盐酸盐

盐酸狄布卡因

2-丁氧基-N-(2-二乙氨基乙基)-4-喹啉羧基酰胺盐酸盐

盐酸地布卡因

英文名称:

2-butoxy-n-(2-(diethylamino)ethyl)-cinchoninamid monohydrochloride

2-butoxy-n-(2-diethylaminoethyl)cinchoninamide hydrochloride

2-butoxy-n-(2-diethylaminoethyl)cinchoninic acid amide hydrochloride

2-n-butoxy-n-(2-diethylaminoethyl)cinchoninamide hydrochloride

2-butoxy-n-(2-(diethylamino)ethyl)-4-quinolinecarboxamid monohydrochlorid

benzolin (local anesthetic)

butoxycinchoninic acid diethylethylenediamide hydrochloride

c 3225

cincaine chloride

cincaine hydrochloride

cinchocaine hydrochloride

cinchocainium chloride

cinchokain hydrochlorid

dibucaine hydrochloride

nupercaine hydrochloride

percain

percaine

percamin s

sovcain

sovcaine

4-Quinolinecarboxamide,2-butoxy-N-[2-(diethylamino)ethyl]-,monohydrochloride

Hibucaine hydrochloride

2-Butoxy-N-(2-diethylaminoethyl)-4-quinolinecarboxamide hydrochloride

dibucainehydrochloride

展开更多英文名

性质描述:

白色结晶性粉末。熔点94-96℃。易溶于水（1份该品溶于0.5份水），极易溶于乙醇、丙酮、氯仿，微溶于苯，不溶于醚。味略苦，有潮解性，遇光变质。

生产方法:

2-羟基喹啉羧酸经氯化、缩合、丁醚化、成盐得到辛可卡因。

用途:

该品属酰胺类麻醉药，临床应用的局麻药中，辛可卡因是作用最强、毒性最大、维持时间最长的一种。注射给药的麻醉强度是普鲁卡因的15倍，毒性也大15倍。起效较慢，约15min，但持续作用时间为普鲁卡因的3倍。局部刺激性小，穿透力较强。用于表面麻醉、浸润麻醉或硬脊膜外麻醉。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

C2177000

Cinchocaine hydrochloride

European Pharmacopoeia (EP) Reference Standard

1277.32元/ ;

展开

产品说明

一般描述

Cinchocaine hydrochloride is a drug commonly used in ophthalmic ointments to produce conjunctival anaesthesia or in dilute penetrable solutions to produce spinal or surface anesthesia.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Cinchocaine hydrochloride may be used as a reference standard for the determination of chlorpromazine and thioridazine hydrochlorides in pharmaceutical formulations by high performance liquid chromatographic method.

生化/生理作用

强效、长效局部麻醉剂

包装

Unit quantity: 60 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₀H₂₉N₃O₂ · HCl
分子量	379.92
MDL编号	MFCD00012735
PubChem化学物质编号	329774974
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
mp	99-101 ℃ (lit.)
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	Cl[H].CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1
InChI	1S/C20H29N3O2.ClH/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3;/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24);1H
InChI key	IVHBBMHQKZBJEU-UHFFFAOYSA-N
Gene Information	human ... SCN10A(6336), SCN5A(6331)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

D0638

Supelco

Dibucaine hydrochloride

analytical standard, ≥99%

694.22元/1 G; 2223.58元/5 G; 6797.24元/25 G;

展开

产品说明

一般描述

Dibucaine hydrochloride is a quinolone derivative, which can be prepared using isatin as the starting material followed by a series of reactions. It is a local anesthetic agent.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

包装

1, 5, 25 g in glass bottle

生化/生理作用

强效、长效局部麻醉剂

基本信息

经验(实验)分子式	C₂₀H₂₉N₃O₂ · HCl
分子量	379.92
EC 号	200-498-1
MDL编号	MFCD00012735
PubChem化学物质编号	24893282
NACRES	NA.24

产品性质

等级	analytical standard
质量水平	200
测定	≥99%
technique(s)	HPLC: suitable gas chromatography (GC): suitable
mp	99-101 ℃ (lit.)
application(s)	forensics and toxicology pharmaceutical (small molecule)
格式	neat
SMILES string	Cl[H].CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1
InChI	1S/C20H29N3O2.ClH/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3;/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24);1H
InChI key	IVHBBMHQKZBJEU-UHFFFAOYSA-N
Gene Information	human ... SCN10A(6336), SCN5A(6331)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Faceshields, Gloves

1187003

USP

Dibucaine hydrochloride

United States Pharmacopeia (USP) Reference Standard

3231.47元/500 MG;

展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

强效、长效局部麻醉剂

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₀H₂₉N₃O₂ · HCl
分子量	379.92
MDL编号	MFCD00012735
PubChem化学物质编号	329749369
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	USP
mp	99-101 ℃ (lit.)
application(s)	pharmaceutical (small molecule)
格式	neat
SMILES string	Cl[H].CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1
InChI	1S/C20H29N3O2.ClH/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3;/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24);1H
InChI key	IVHBBMHQKZBJEU-UHFFFAOYSA-N
Gene Information	human ... SCN10A(6336), SCN5A(6331)

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H318
预防措施声明	P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
危险分类	Acute Tox. 4 Oral - Eye Dam. 1
储存分类代码	6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable