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CAS: 72-44-6
分子式: C16H14N2O
分子量: 250.29
中文名称: 
2-甲基-3-(2-甲基苯基)-4(3H)喹唑啉酮
安眠酮
2-甲基-3-邻甲苯基喹唑酮-[4]
甲苯喹唑酮
海米那
眠可欣
甲喹酮
英文名称: 
optimil
qz-2
qz 2
quaalude
pro-dorm
parminal
parest
ortonal
orthonal
optinoxan
revonal
omnyl
normi-nox
noctilene
nobedorm
nethaqualone
mtq
mozambin
motolon
mollinox
sopor
2-Methyl-3-o-toly-4(3H)-quinazolinone
2-Methyl-3-(2-methylphenyl)-4(3H)-quinazoli-none
Methapualone
4(3H)-Quinazolinone,2-methyl-3-(2-methylphenyl)-
tuazolone
tuazole
tr-495
torinal
soverin
metolquizolone
sonal
somnomed
somnafac
somberol
sindesvel
rouqualone
roulone
rorer 148
ric 272
2-methyl-3-o-tolyl-4(3h)-chinazolone
cn 38703
citexal
ci-705
cateudyl
2-methyl-3-(2-methylphenyl)-4(3h)-quinazolinon
3,4-dihydro-2-methyl-4-oxo-3-o-tolylquinazoline
2-methyl-3-tolyl-4-oxybensdiazine
2-methyl-3-o-tolyl-4-quinazolone
2-methyl-3-o-tolyl-4(3h)-quinazolinone
dormigoa
2-methyl-3-o-tolyl-4(3h)-chinazolinon (german)
2-methyl-3-o-tolyl-4(3h)-chinazolinon
2-methyl-3-(o-tolyl)-3,4-dihydro-4-quinazolinone
2-methyl-3-(2-tolyl)quinazol-4-one
2-methyl-3-(2-methylphenyl)-4-quinazolinone
2-methyl-3-(2-methylphenyl)-4(3h)-quinazolinone
(2-methyl-3-(o-tolyl)-3,4-dihydro-4-(quinazolinone)
2-methyl-3-o-tolyl-4(3h)-quinazolinon
Methaqualone
hyptor base
methaqualoneinone
metaqualon
metachalon
mequin
melsomin
melsedin base
maoa
mandrax
ipnofil
2-methyl-3-(2-methylphenyl)-4(3H)-Quinazolinone
hyptor
hypcol
hyminal
holodorm
fadormir
dorsedin
dormutil
dormogen
性质描述: 白色结晶性粉末。熔点为120℃(114-116℃)。易溶于氯仿、乙醇、乙醚、丙酮,不溶于水。无臭,味微苦。
生产方法: 由邻乙酰氨基苯甲酸(见00150)与邻氨基甲苯环合而成。将邻乙酰氨基苯甲酸的甲苯溶液在80℃、搅拌下加入邻氨基甲苯,再滴加三氯化磷甲苯溶液,回流反应即生成甲喹酮。
用途: 本品为非苯二氮类催眠药。作用快而较强,一般在服药后20-30min内发生作用。持续6-8h。本品自消化道吸收后几乎全部在肝脏内代谢,经肾排出。它除排出。它除具有镇静催眠作用外,还有抗惊厥、解痉、局部麻醉和较弱的抗组胺作用。大鼠口服LD50为255mg/kg。
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