CAS 78-41-1; 2-(p-chlorophenyl)-1-(p-(2-(diethylamino)ethoxy)phenyl)-1-p-tolyl-ethano

CAS:

78-41-1

分子式:

C₂₇H₃₂NO₂Cl

分子量:

438.00

熔点:

102.9 - 103.7 °C

英文名称:

2-(p-chlorophenyl)-1-(p-(2-(diethylamino)ethoxy)phenyl)-1-p-tolyl-ethano

1-(4-(2-(diethylamino)ethoxy)phenyl)-1-(p-tolyl)-2-(p-chlorophenyl)ethan ol

1-(p-(beta-diethylaminoethoxy)phenyl)-1-(p-tolyl)-2-(p-chlorophenyl)etha nol

2-(p-chlorophenyl)-1-(p-(beta-diethylaminoethoxy)phenyl)-1-(p-tolyl)etha nol

2-p-chlorophenyl-1-(p-(2-diethylaminoethoxy)phenyl)-1-p-tolylethanol

alpha-(p-chlorobenzyl)-4-diethylaminoethoxy-4'-methylbenzhydrol

mer 29

metasqualene

nsc 65345

triparanol

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

T921021

MACKLIN

曲帕拉醇

≥97% (HPLC)

2478元/5mg;

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储存：2-8°C
状态：粉末

T5200

Sigma-Aldrich

Triparanol

≥97% (HPLC), powder

2410.17元/5 MG; 7378.78元/25 MG;

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产品说明

应用

Triparanol has been used to inhibit cholesterol biosynthesis in lipid rafts¹. Triparanol has also been used as a 3β-hydroxysterol-Δ24-reductase inhibitor to study its effect on delayed-rectifier potassium current (I_ks) channels².

包装

5, 25 mg in glass bottle

生化/生理作用

Triparanol is known to repress Hedgehog signaling in cancer cells and can also inhibit tumor growth³.
Desmosterol Delta24 (D24) reductase inhibitor.

制备说明

Triparanol is soluble in DMSO at 20 mg/ml and is also soluble in alcohol. It is slightly soluble in olive oil and is insoluble in water.

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T5200.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

经验(实验)分子式	C₂₇H₃₂NO₂Cl
分子量	438.00
EC 号	201-115-0
MDL编号	MFCD00865748
PubChem化学物质编号	24724632
NACRES	NA.77

产品性质

质量水平	100
测定	≥97% (HPLC)
形式	powder
颜色	white to off-white
mp	102.9-103.7 ℃
溶解性	DMSO: 20 mg/mL H₂O: insoluble alcohol: soluble olive oil: slightly soluble
储存温度	2-8℃
SMILES string	CCN(CC)CCOc1ccc(cc1)C(O)(Cc2ccc(Cl)cc2)c3ccc(C)cc3
InChI	1S/C27H32ClNO2/c1-4-29(5-2)18-19-31-26-16-12-24(13-17-26)27(30,23-10-6-21(3)7-11-23)20-22-8-14-25(28)15-9-22/h6-17,30H,4-5,18-20H2,1-3H3
InChI key	SYHDSBBKRLVLFF-UHFFFAOYSA-N
Gene Information	human ... DHCR24(1718), EBP(10682)

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H318
预防措施声明	P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
危险分类	Acute Tox. 4 Oral - Eye Dam. 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves