重组人源ApolipoProtein E/APOE Protein, His Tag
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产品名称 APOE重组蛋白 重组蛋白APOE 产品介绍
Catalog Number KMH686 Product Name Recombinant Human ApolipoProtein E/APOE Protein, His Tag Alias AD2, LPG, APO-E, ApoE4, LDLCQ5, apolipoprotein E Size 50μg, 100μg Species Human Host Mammalian Cells Source This protein contains the human APOE(Lys19-His317) was fused with the C-terminal His Tag and expressed in Mammalian cells. Uniprot Accession P02649 Purity ≥90% as determined by SDS-PAGE Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method. Buffer PBS Predicted Molecular Weight 32.89kDa Background The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants. Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. Shipping Condition This product is shipped on ice packs or dry ice. For Research Use Only 用户评论 产品评分 目前评分共0人 产品质量
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