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DEPDC5抗体
产品介绍 靶标: DEPDC5 产品别名: DEP.5; FFEVF; FFEVF1; DEPDC5; DEP domain containing 5, GATOR1 subcomplex subunit; DEP domain containing 5, GATOR1 subcomplex subunit; GATOR complex protein DEPDC5; DEP domain-containing protein 5; 背景信息: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway. 宿主:Rbt |
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