抗体 >> 其他抗体
驱动蛋白家族蛋白7抗体
产品介绍 靶标: Kif7 产品别名: Kif7; kinesin family member 7; kinesin family member 7; kinesin-like protein KIF7; kinesin 7; 驱动蛋白家族蛋白7; 背景信息: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011], 宿主:Rbt |
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