产品介绍 靶标: Mhc 产品别名: Bsh; CG17927; DROMHC; Dm II; DmMHC; Dmel\CG17927; DroMII; Ifm(2)2; Ifm(2)RU1; MHC; MRP; Mhc36B; Mrp; MyHC; Myo; Myo6; Nup; Sht; Stp; chr2L:16765388..16765564; chr2L:16781880..16782040; ifm(2)2; ifm(2)RU1; ifm(2)RU2; l(2)36Ae; l(2)M66; l(2)k10423; mMHC; mhc; sMHC; Mhc; Myosin heavy chain; Myosin heavy chain; myosin heavy chain; CG17927-PA; CG17927-PB; CG17927-PC; CG17927-PD; CG17927-PE; CG17927-PF; CG17927-PG; CG17927-PH; CG17927-PI; CG17927-PK; CG17927-PL; CG17927-PM; CG17927-PN; CG17927-PO; CG17927-PP; CG17927-PQ; CG17927-PR; CG17927-PS; CG17927-PT; CG17927-PU; CG17927-PV; Mhc-PA; Mhc-PB; Mhc-PC; Mhc-PD; Mhc-PE; Mhc-PF; Mhc-PG; Mhc-PH; Mhc-PI; Mhc-PK; Mhc-PL; Mhc-PM; Mhc-PN; Mhc-PO; Mhc-PP; Mhc-PQ; Mhc-PR; Mhc-PS; Mhc-PT; Mhc-PU; Mhc-PV; Not-upheld; Shrunken-thorax; beta-myosin heavy chain; chain; heavy chain; indirect flight muscle (2) RU1; indirect flight muscle (2) RU2; muscle myosin; muscle myosin II; muscle myosin II heavy chain; muscle myosin heavy chain; muscle myosin-II; muscle specific myosin II; myosin; myosin HC; myosin II heavy chain; myosin heavy; myosin heavy Chain-PF; myosin heavy-chain; myosin heavy-chain protein; myosin rod protein; myosin-heavy chain; samba; sarcomeric myosin heavy-chain; shrunken thorax; stuckup; 背景信息: Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008] 宿主:Rbt |
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