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双氧化酶1/甲状腺氧化酶1抗体
产品介绍 靶标: DUOX1 产品别名: LNOX1; NOXEF1; THOX1; DUOX1; dual oxidase 1; dual oxidase 1; dual oxidase 1; NADPH thyroid oxidase 1; flavoprotein NADPH oxidase; large NOX 1; long NOX 1; nicotinamide adenine dinucleotide phosphate oxidase; thyroid oxidase 1; 双氧化酶1/甲状腺氧化酶1; 背景信息: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2012], 宿主:Rbt |
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