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突触结合蛋白2抗体
产品介绍 靶标: NECAB2 产品别名: EFCBP2; stip-2; NECAB2; N-terminal EF-hand calcium binding protein 2; N-terminal EF-hand calcium binding protein 2; N-terminal EF-hand calcium-binding protein 2; EF-hand calcium-binding protein 2; neuronal calcium binding 2; neuronal calcium-binding protein 2; synaptotagmin-interacting protein 2; 突触结合蛋白2; 背景信息: NECAB2 (N-Terminal EF-Hand Calcium Binding Protein 2) is a Protein Coding gene. The NECAB2 gene, located on 16q23.3, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. The protein encoded by this gene is a neuronal calcium-binding protein that binds to and modulates the function of at least two receptors, adenosine A(2A) receptor and metabotropic glutamate receptor type 5. NECAB2 may act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation. 220 organisms have orthologs with the human gene NECAB2. 宿主:Rbt |
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