产品介绍 靶标: NUDT11 产品别名: APS1; ASP1; DIPP3b; DIPP3beta; hDIPP3beta; NUDT11; nudix hydrolase 11; nudix hydrolase 11; diphosphoinositol polyphosphate phosphohydrolase 3-beta; DIPP-3-beta; DIPP3-beta; diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta; diadenosine hexaphosphate hydrolase (AMP-forming); diphosphoinositol polyphosphate phosphohydrolase 3, beta; hAps1; nucleoside diphosphate-linked moiety X motif 11; nudix (nucleoside diphosphate linked moiety X)-type motif 11; nudix motif 11; 背景信息: NUDT11 (Nudix Hydrolase 11) is a Protein Coding gene. It is located on Xp11.22. NUDT11 belongs to a subgroup of phosphohydrolases that preferentially attack diphosphoinositol polyphosphates. Diseases associated with NUDT11 include Encephalitozoonosis. Among its related pathways are Metabolism and Inositol phosphate metabolism (REACTOME). The hDIPP3 genes (NUDT10 encodes hDIPP3alpha; NUDT11 encodes hDIPP3beta) are only 152 kbp apart at p11.22 on chromosome X and probably arose by duplication. Transcription of both genes is inactivated on one of the X chromosomes of human females to maintain appropriate gene dosage. The hDIPP3 pair add tissue-specific diversity to the molecular mechanisms regulating diphosphoinositol polyphosphate turnover. 27 organisms have orthologs with the human gene NUDT11. 宿主:Rbt |
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