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细胞纤毛内转运同源蛋白122抗体
产品介绍 靶标: IFT122 产品别名: CED; CED1; FAP80; SPG; WDR10; WDR10p; WDR140; IFT122; intraflagellar transport 122; intraflagellar transport 122; intraflagellar transport protein 122 homolog; WD repeat domain 10; WD repeat-containing protein 10; WD repeat-containing protein 140; intraflagellar transport 122 homolog; 细胞纤毛内转运同源蛋白122; 背景信息: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Mutations in this gene cause cranioectodermal dysplasia-1. A related pseudogene is located on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013], 宿主:Rbt |
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