RNA结合蛋白25抗体

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RNA结合蛋白25抗体


交货期:	1周
产品别名:	Anti-RBM25 Anti-RNA binding motif protein 25 Antibody

产品介绍

靶标：

RBM25

产品别名：

NET52； RED120； RNPC7； S164； Snu71； fSAP94； RBM25； RNA binding motif protein 25； RNA binding motif protein 25； RNA-binding protein 25； Arg/Glu/Asp-rich protein, 120 kDa； RNA-binding region (RNP1, RRM) containing 7； RNA-binding region-containing protein 7； U1 small nuclear ribonucleoprotein 1SNRP homolog； arg/Glu/Asp-rich protein of 120 kDa； functional spliceosome-associated protein 94； RNA结合蛋白25；

背景信息：

RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。