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细胞膜蛋白Derlin抗体
产品介绍 靶标: Derl1 产品别名: 1110021N07Rik; AI195141; AW551338; Derlin-1; Derl1; Der1-like domain family, member 1; Der1-like domain family, member 1; derlin-1; degradation in endoplasmic reticulum protein 1; der1-like protein 1; 细胞膜蛋白Derlin; 背景信息: derlin 1(DERL1) Homo sapiens The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012], 宿主:Rbt |
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