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LRWD1蛋白抗体
产品介绍 靶标: Lrwd1 产品别名: 1200011O22Rik; AU042569; AW548074; Orca; Lrwd1; leucine-rich repeats and WD repeat domain containing 1; leucine-rich repeats and WD repeat domain containing 1; leucine-rich repeat and WD repeat-containing protein 1; ORC-associated protein; origin recognition complex-associated protein; LRWD1蛋白; 背景信息: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015], 宿主:Rbt |
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