FAM123A蛋白抗体

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FAM123A蛋白抗体


交货期:	1周
产品别名:	Anti-Amer2 Anti-APC membrane recruitment 2 Antibody

产品介绍

靶标：

Amer2

产品别名：

2600011E07Rik； Fam123a； Amer2； APC membrane recruitment 2； APC membrane recruitment 2； APC membrane recruitment protein 2； family with sequence similarity 123, member A； protein FAM123A； FAM123A蛋白；

背景信息：

Amer2 (APC membrane recruitment 2; FAM123A) is a direct interaction partner of adenomatous polyposis coli (APC), related to the tumor suppressor Amer1/WTX. FAM123A interacts with APC via two domains that bind the Armadillo repeats of APC. These domains are conserved in the related proteins Amer1/WTX (Wilms tumor gene on the X-chromosome; FAM123B), which acts as a negative regulator of Wnt signaling, and Amer3 (FAM123C). Amer1 is mutated in Wilms tumors and in the inherited disease osteopathia striata congenita with cranial sclerosis. Amer2 negatively regulates Wnt signaling probably by interfering with β-catenin.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。