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Spsb1抗体
产品介绍 靶标: Spsb1 产品别名: 1110014L01Rik; 4930422J18Rik; AI596360; AI854583; SSB-1; SSB1; Spsb1; splA/ryanodine receptor domain and SOCS box containing 1; splA/ryanodine receptor domain and SOCS box containing 1; SPRY domain-containing SOCS box protein 1; SPRY domain-containing SOCS box protein SSB-1; 背景信息: Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Negatively regulates nitric oxide (NO production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2. Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5. 宿主:Rbt |
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