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SHISA4蛋白抗体
SHISA4蛋白抗体图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Shisa同源物4(SHISA4)抗体
Anti-Shisa4
产品介绍
靶标:

Shisa4


产品别名:

9330132O05Rik; Tmem58; mShisa4; Shisa4; shisa family member 4; shisa family member 4; protein shisa-4; shisa homolog 4; transmembrane protein 58; SHISA4蛋白; Shisa同源物4(SHISA4);


背景信息:
SHISA4 Antibody: SHISA4 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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