FOXRED2蛋白抗体

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FOXRED2蛋白抗体


交货期:	1周
产品别名:	Anti-FOXRED2 Anti-FAD dependent oxidoreductase domain containing 2 Antibody

产品介绍

靶标：

FOXRED2

产品别名：

ERFAD； FOXRED2； FAD dependent oxidoreductase domain containing 2； FAD dependent oxidoreductase domain containing 2； FAD-dependent oxidoreductase domain-containing protein 2； ER flavoprotein associated with degradation； endoplasmic reticulum flavoprotein associated with degradation； FOXRED2蛋白；

背景信息：

FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。