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SGOL2蛋白抗体
产品介绍 靶标: SGO2 产品别名: SGOL2; TRIPIN; SGO2; shugoshin 2; shugoshin 2; shugoshin 2; shugoshin-like 2; SGOL2蛋白; 背景信息: function:During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity). May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the shugoshin family.,subcellular location:In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase.,subunit:Directly interacts with PPP2CA., 宿主:Rbt |
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