重组RAGEF2蛋白

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重组RAGEF2蛋白


交货期:	1周
产品别名:	Recombinant RAPGEF6 Recombinant Rap guanine nucleotide exchange factor 6 protein

产品介绍

基因名：

RAPGEF6

产品别名：

KIA001LB； PDZ-GEF2； PDZGEF2； RA-GEF-2； RAGEF2； RAPGEF6； Rap guanine nucleotide exchange factor 6； Rap guanine nucleotide exchange factor 6； rap guanine nucleotide exchange factor 6； PDZ domain containing guanine nucleotide exchange factor (GEF) 2； PDZ domain-containing guanine nucleotide exchange factor 2； PDZ domain-containing guanine nucleotide exchange factor I； Rap guanine nucleotide exchange factor (GEF) 6； RAGEF2蛋白；

背景信息：

RAPGEF6 is a guanine nucleotide exchange factor (GEF) that is expressed in a variety of tissues. Localizing to the cytoplasm and translocated to the plasma membrane upon ligand binding, RAPGEF6 contains an N-terminal Ras-GEF domain, a cyclic nucleotide monophosphate-binding domain, a PDZ (PSD-95/DlgA/ZO-1) domain, a Ras-associating (RA) domain and a Ras exchanger motif. RAPGEF6 is closely related to RAPGEF2 and both proteins exhibit GEF activity specific towards Rap 1 and Rap 2. In addition, RAPGEF6 is capable of binding to M-Ras via its RA domain. Due to alternative splicing events, two additional isoforms exist for RAPGEF6, namely PDZ-GEF2A and PDZ-GEF2B.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。