蛋白质/抗原/多肽 >> 重组蛋白
重组锌指蛋白抑制NFκB蛋白
产品介绍 基因名： RNF216 产品别名： CAHH； TRIAD3； U7I1； UBCE7IP1； ZIN； RNF216； ring finger protein 216； ring finger protein 216； E3 ubiquitin-protein ligase RNF216； RING-type E3 ubiquitin transferase RNF216； triad domain-containing protein 3； ubiquitin-conjugating enzyme 7-interacting protein 1； zinc finger protein inhibiting NF-kappa-B； 锌指蛋白抑制NFκB蛋白； 背景信息： The TRIAD3 gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. 标签：His-tag |
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