蛋白质/抗原/多肽 >> 重组蛋白
重组CNOT6蛋白
产品介绍 基因名: CNOT6 产品别名: CCR4; Ccr4a; CNOT6; CCR4-NOT transcription complex subunit 6; CCR4-NOT transcription complex subunit 6; CCR4-NOT transcription complex subunit 6; carbon catabolite repression 4 protein; carbon catabolite repressor protein 4 homolog; cytoplasmic deadenylase; CNOT6蛋白; 细胞表面趋化因子受体4相关蛋白6; 背景信息: CNOT6 is a widely expressed subunit of the CCR4-NOT transcription complex. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription as well as mRNA degradation. Various subunits (e.g. CNOT1, CNOT3) are involved in influencing nuclear hormone receptor activities. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome. CNOT6 belongs to the CCR4/nocturin family and contains three LRR (leucine-rich) repeats. In the cytoplasm, CNOT6 acts as a poly(A) nuclease involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the Fos gene. 标签:His-tag |
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