蛋白质/抗原/多肽 >> 重组蛋白
重组ATP依赖的解旋酶CHD8蛋白
产品介绍 基因名: CHD8 产品别名: AUTS18; HELSNF1; IDDAM; CHD8; chromodomain helicase DNA binding protein 8; chromodomain helicase DNA binding protein 8; chromodomain-helicase-DNA-binding protein 8; ATP-dependent helicase CHD8; axis duplication inhibitor; duplin; helicase with SNF2 domain 1; ATP依赖的解旋酶CHD8; 染色质域解旋酶DNA结合蛋白8(CHD8); 背景信息: This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010] 标签:His-tag |
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