产品介绍 基因名: POMGNT2 产品别名: AGO61; C3orf39; GTDC2; MDDGA8; MDDGC8; POMGNT2; protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-); protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-); protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2; glycosyltransferase-like domain containing 2; glycosyltransferase-like domain-containing protein 2; protein O-mannose beta-1,4-N-acetylglucosaminyltransferase 2; 3号染色体开放阅读框39; 背景信息: C3orf39, also known as AGO61, is a 580 amino acid secreted protein belonging to the glycosyltransferase 61 family. C3orf39 is encoded by a gene that maps to human chromosome 3p25.1. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3. 标签:His-tag |
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