蛋白质/抗原/多肽 >> 重组蛋白
重组锌指蛋白461
产品介绍 基因名: ZNF461 产品别名: GIOT-1; GIOT1; HZF28; ZNF461; zinc finger protein 461; zinc finger protein 461; zinc finger protein 461; gonadotropin-inducible ovary transcription repressor 1; zinc finger protein 28; 锌指蛋白461; 背景信息: ?GIOT-1 is a 563 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events. 标签:His-tag |
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