| CAS NO: | 150973-78-7 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 150973-78-7 |
| 化学名 | 3-ethyl-4-hydroxy-6-(1-methylethyl)-2H-pyran-2-one |
| Canonical SMILES | O=C1OC(C(C)C)=CC(O)=C1CC |
| 分子式 | C10H14O3 |
| 分子量 | 182.2 |
| 溶解度 | DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Germicidin is a pyranone antibiotic originally excreted by Streptomyces viridochromogenes NRRL B-1551. Germicidin has an inhibitory effect on the germination of its own arthrospores at a concentration as low as 200 pM (40 pg/ml). Higher concentrations of germicidin inhibited porcine Na+/K+-activated ATPase and retarded the germination of the cress Lepidium sativum with an ID50 of 100 μM. Germicidin was the first known autoregulative inhibitor of spore germination in the genus Streptomyces and was isolated from the supernatant of germinated spores, but also from the supernatant of the submerged culture [1]. Germicidins B inhibited germination of S. coelicolor A3(2) spores above 1 μg/ml. The S. coelicolor A3(2) spores collected from a single petri dish (9 cm i.d.) contained 5.4 μg of germicidin A (~2.7 × 10-14 g per spore) and contents of germicidins B, C and D were 0.2–0.8 μg. The activity of the spore extract corresponded well with the sum of the activity of each germicidin. Germicidins functioned as self-germination inhibitors in S. coelicolor A3(2) [2]. References: |
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