Parthenolide, formerly known as NSC-157035, is a novel sesquiterpene lactone isolated from the medicinal herb Feverfew, acting as a NF-κB activation inhibitor potentially for the
treatment of cancer. Parthenolide induces apoptosis and autophagy-mediated growth inhibition in HeLa cells by suppressing the PI3K/Akt signaling pathway and mitochondrial membrane depolarization and ROS generation.
纯度:≥98%
CAS:20554-84-1