| CAS NO: | 80-08-0 |
| 包装: | 1mg |
| 市场价: | 1187元 |
| Cas No. | 80-08-0 |
| 别名 | 氨苯砜; 4,4′-Diaminodiphenyl sulfone; DDS |
| 化学名 | 4,4'-sulfonyldianiline |
| Canonical SMILES | NC1=CC=C(S(C2=CC=C(N)C=C2)(=O)=O)C=C1 |
| 分子式 | C12H12N2O2S |
| 分子量 | 248.3 |
| 溶解度 | ≥ 8.35mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.Target: AntibacterialDapsone is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). Dapsone antagonized all of the I/R end points measured, showing a remarkable ability to decrease markers of damage through antioxidant, antiinflammatory, and anti-apoptotic effects [1]. As an antibacterial, dapsone inhibits bacterial synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthetase. Dapsone has anti-inflammatory and immunomodulatory effects [2]. References: |
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