| CAS NO: | 773-76-2 |
| 包装: | 50mg |
| 市场价: | 494元 |
| Cas No. | 773-76-2 |
| 别名 | 氯喔星 |
| 化学名 | 5,7-dichloroquinolin-8-ol |
| Canonical SMILES | C1=CC2=C(C(=C(C=C2Cl)Cl)O)N=C1 |
| 分子式 | C9H5Cl2NO |
| 分子量 | 214.05 |
| 溶解度 | ≥ 9.7mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp[1][2]. By using the Jouyban-Acree model, the Chloroxine solubility is well correlated obtaining RAD values lower than 3.64% and RMSD values lower than 8.82 × 10–6. Chloroxine is preferentially solvated by water for the studied mixtures in water-rich compositions; while within intermediate and co-solvent-rich compositions, Chloroxine is preferentially solvated by DMSO (DMF, NMP or 1,4-dioxane) in DMSO (DMF, NMP or 1,4-dioxane) + water mixtures. It is shown that the change in solvent-solvent interaction energy accounted by cavity term governed the solubility variation of Chloroxine in all aqueous mixtures[1]. References: |
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