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Pelubiprofen-13C,d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pelubiprofen-13C,d3图片
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Pelubiprofen-13C,d3 是一种 13C- 和氘代标记的 Pelubiprofen。Pelubiprofen 是一种具有口服活性,非甾体类抗炎药,是 2-芳基丙酸家族的成员,对COX-2的活性具有相对选择性的作用。Pelubiprofen 抑制 COX 活性和 TGF-β 活化的激酶 1-IκB 激酶 β-NF-κB 途径,并具有显着的抗炎和缓解疼痛作用。
生物活性

Pelubiprofen-13C,d3 is the 13C- and deuterium labeled Pelubiprofen. Pelubiprofen, an orally active and non-steroidal anti-inflammatory drug, is a member of the 2-arylpropionic acid family and has relatively selective effects onCOX-2activity. Pelubiprofen inhibitsCOXactivity and thetransforming growth factor-βactivated kinase 1-IκB kinase β-NF-κB pathway, and has significant anti-inflammatory and analgesic effects[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[29].

分子量

262.32

Formula

C1513CH15D3O3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.