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Penicillin V
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Penicillin V图片
CAS NO:87-08-1
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
Phenoxymethylpenicillin
产品介绍
Penicillin V (Phenoxymethylpenicillin) 是一种有效且具有口服活性的抗生素。Penicillin V 对 链球菌,艰难梭菌和金黄色葡萄球菌显示出抗菌活性。Penicillin V 具有研究中耳炎、鼻窦炎、咽炎和扁桃体炎的潜力[ 4]
生物活性

Penicillin V (Phenoxymethylpenicillin) is a potent and orally activeantibiotic. Penicillin V shows antibacterial activity forStreptococci,Clostridium difficileandstaphylococcus aureus. Penicillin V has the potential for the research of otitis, sinusitis, pharyngitis and tonsillitis[1][2][3][4].

体外研究
(In Vitro)

Penicillin V (0.002-8.0 mg/L) inhibits the growth ofStreptococci, with the minimum inhibitory concentrations (MICs) of 0.004-0.008 mg/L[2].
Penicillin V (0.002-8.0 mg/L) shows antibacterial activity forClostridium difficilewith an MIC50value of 4.0 mg/L and an MIC90value of 8.0 mg/L[3].
Penicillin V (0.004-0.063 mg/L; 18 h) inhibits the growth ofStaphylococcus aureus, with an MIC value of 0.016 mg/L[4].

体内研究
(In Vivo)

Penicillin V (0.063-0.25 mg/kg; s.c.) inhibits the outgrowth ofS. aureusin mice thigh muscle[4].
Penicillin V (2 mg/kg; s.c.) exhibits the plasma half-life (61 min) and mean AUC (0.47 mg/L·h)[4].
Penicillin V (100 mg/kg; p.o. once daily for 5 d) avoids the fulminant infection of acute purulent otitis media (AOM) in rats[5].

Animal Model:Specific pathogen free (SPF) male Swiss mice (20-25 g) are inoculatedS. aureus[4]
Dosage:0.063, 0.13, 0.25 mg/kg
Administration:S.c.
Result:Decreased the number of CFU (1.34×107counts/mL) compared to controls (3.5×107counts/mL) at the dose of 0.25 mg/kg.
Clinical Trial
分子量

350.39

Formula

C16H18N2O5S

CAS 号

87-08-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.