| CAS NO: | 56-10-0 |
| 包装: | 25g |
| 市场价: | 305元 |
| Cas No. | 56-10-0 |
| 别名 | 乙胺硫脲,Antiradon,NSC 22877 |
| 化学名 | 2-aminoethyl carbamimidothioate, dihydrobromide |
| Canonical SMILES | N/C(SCCN)=N/[H].Br.Br |
| 分子式 | C3H9N3S · 2HBr |
| 分子量 | 281.0 |
| 溶解度 | ≤10mg/ml in Water |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | S-(2-aminoethyl) Isothiourea (dihydrobromide) is a potent and non-selective inhibitor of NOS with Ki values of 1.8, 2.1, and 0.59 μM for human nNOS, eNOS, and iNOS, respectively [1]. In the brain, nitric oxide (NO), which is synthesized from L-arginine (Arg) by NO synthase (NOS), acts as both an intra- and an intercellular second messenger. Nitric oxide synthase (iNOS, eNOS, and nNOS) catalyzed the production of NO in the two-step oxidation of L-arginine. The three isozymes produce NO in separate tissues for different purposes in both normal and diseased states [1]. S-(2-aminoethyl) Isothiourea is a potent and non-selective NOS inhibitor with Ki values of 1.8, 2.1, and 0.59 μM for human nNOS, eNOS, and iNOS, respectively [1]. Reference: |
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