DFP00173 is a highly potent and specific aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ~0.1-0.4 μM. DFP00173 is specific for AQP3 over the homologous AQP isoforms AQP7 and AQP9. References: [1]. Sonntag Y, et al. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors. J Biol Chem. 2019 May 3;294(18):7377-7387.

纯度：≥98%

CAS：672286-03-2