Magnolol 是RXRα和PPARγ的激动剂，EC50值分别为 10.4 μM 和 17.7 μM。他是从厚朴的树皮中分离得到的一种木脂素。

Magnolol is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.

Magnolol shows significant inhibitory activities against Trichophyton mentagrophytes, Microsporium gypseum, Epidermophyton floccosum, Aspergillus niger, Cryptococcus neoformans, and Candida albicans with minimum inhibitory concentrations (MIC) in a range of 25-100 μg/ml.

528-43-8

C18H18O2

266.34

5,5'-Diallyl-2,2'-biphenyldiol;厚朴酚;NSC 293099

Ethanol:49 mg/mL (184 mM)
DMSO:49 mg/mL (184 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years