Lappaconite HBr 是天然生物碱类化合物,具有抗心律失常作用。
产品描述
Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai. It has anti-inflammatory effects.
体外活性
Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects. Its absorption percentage in rat stomachs after administration was 9.67%.The absorption percentages at duodenum,jejunum,ileum and colon were 19.61%,11.83%,12.95% and 9.51%, respectively.When the concentration was raised from 10 mg/L to 40 mg/L, the uptake of lappaconite hydrobromide was linearly increased,whereas the absorption rate constant kept at the same level. [1]
体内活性
LD50: Mice 10.5 mg/kg (i.p.); Rats 9.9 mg/kg (i.p.) [2]
Cas No.
97792-45-5
分子式
C32H45BrN2O8
分子量
665.622
别名
Lappaconite HBr;氢溴酸高乌甲素;Allapinine
储存和溶解度
Ethanol:<1 mgml
DMSO:28 mg/mL (42.06 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years