FT001是一种有效的、选择性的和具有口服活性的 BET Bromodomain抑制剂，具有抗肿瘤活性。FT001抑制MYC的表达，IC50为0.46 μM。FT001对MV-4-11具有有效的抗增殖作用，并在体外和体内显著抑制MYC mRNA水平。

FT001 is a potent, selective and orally available inhibitor of BET Bromodomain with antitumor activity. FT001 inhibited the expression of MYC with the IC50 value of 0.46 μM). FT001 has potent antiproliferative effects against MV-4-11 and demonstrates significant MYC mRNA suppression both in vitro and in vivo.

1778655-51-8

C25H29N3O4S

467.58

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years