Rubitecan 是一种与喜树碱相关的半合成药物，具有有效的抗肿瘤和抗病毒特性。它是一种 DNA 拓扑异构酶 I 抑制剂，以浓度依赖性方式抑制 DNA 拓扑异构酶 I 并在无细胞试验中增加超螺旋 DNA 的比例。

Rubitecan is a DNA topoisomerase I inhibitor. It inhibits DNA topoisomerase I and increases the fraction of supercoiled DNA in a cell-free assay in a concentration-dependent manner.Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties.

91421-42-0

C20H15N3O6

393.35

9-Nitrocamptothecin;RFS 2000;鲁比特康

DMSO:125 mg/mL (317.78 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years