P2Y2R/GPR17 antagonist 1 (Compound 14m) 是一种 P2Y2R 和 GPR17 双重拮抗剂，对 P2Y2R 和 GPR17 的 IC50 值分别为 3.17 μM 和 1.67 μM。P2Y2R/GPR17 antagonist 1 在人肝微粒体中具有极好的代谢稳定性。

P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R and GPR17 antagonist. P2Y2R/GPR17 antagonist 1 shows IC50 values of 3.17 μM and 1.67 μM against P2Y2R and GPR17, respectively. P2Y2R/GPR17 antagonist 1 shows excellent metabolic stability in human liver microsomes.

2395016-49-4

C19H13ClN2O6S

432.83

DMSO:112.5 mg/mL (259.9 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years