IU1-248 是 IU1 的衍生物,是一种选择性 USP14 抑制剂,IC50 为 0.83?μM。
产品描述
IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM[1].
体外活性
IU1-248 exhibits an IC50 value of 0.83?μM toward USP14, which is 10-fold more potent than that of IU1 (IC50=12.25 μM)[1].
Cas No.
2307472-03-1
分子式
C20H23N3O2
分子量
337.42
储存和溶解度
DMSO:80 mg/mL (237.09 mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years