N-Acetyl-D-cysteine 具有抗氧化活性，机制是通过与巯基反应清除ROS。N-Acetyl-D-cysteine不能进入谷胱甘肽代谢途径。

N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.

Consistent with the known stereoselectivity of many biological processes, the unnatural D isomer of N-acetylcysteine failed to increase hepatic glutathione. Liver concentrations remained similar to control suggesting that the D isomer was unable to increase the rate of glutathione synthesis. The D isomer further differed from its L enantiomer in failing to increase the plasma concentration and the urinary excretion of inorganic sulfate. Congruent with these observations, much more N-acetyl-D-cysteine (47% of dose) was recovered unchanged in 24 hr urine than N-acetyl-L-cysteine (6.1% of dose)[2].

26117-28-2

C5H9NO3S

163.2

H2O:250 mg/mL (1531.96 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years