Mirogabalin 是一种高效的、选择性的 α2δ-1 配体，作用于电压敏感性钙通道复合体的α2δ-1亚基。

Mirogabalin is a calcium channel blocker with analgesic effects.

Mirogabalin has potent and sustained analgesic effects (ED50 = 2.5 mg/kg) in rats with diabetes induced by streptozotocin .?Mirogabalin does not inhibit activities associated with CNS adverse effects of analgesics, such as rotarod performance (ID50 = 9.4 mg/kg) or locomotor activity (ID50 = 43.9 mg/kg), at its effective dose.

1138245-13-2

C12H19NO2

209.289

DS5565

DMSO:10mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years