Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM). It is used in the research of the hypertensive disease.

Imidaprilate augments the bradykinin-induced contraction of guinea pig ileum, with AC50 of 1.7 nM.Imidaprilate ?is an active metabolite of 6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM.

Imidaprilate (≥0.2 mg/kg) inhibits angiotensin I (AT-I)-induced pressor response.

89371-44-8

C18H23N3O6

377.39

6366A;Imidaprilat

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years