MMP-12 Inhibitor 是一种选择性的 MMP-12 抑制剂，对人、小鼠、大鼠和绵羊 MMP-12 的 IC50 分别为 2、160、320 和 22.3 nM。

MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.

MMP-12 Inhibitor shows weaker activity against human MMP-3, MMP-13, and MMP-14 with IC50s of 351, 120, and 1100 nM[1].

In mice, MMP-12 Inhibitor (5 mg/kg, p.o.) effectively alleviates rhMMP-12-induced pulmonary inflammatory response by more than 50%[1].

1258003-93-8

C19H20N2O7S

420.44

MMP12;MMP408

DMSO:50 mg/mL (118.9 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years