CDN1163 是肌膜/内质网Ca2+-ATPase (SERCA)的变构激活剂，可改善 Ca2+稳态，可减轻糖尿病和代谢紊乱。

CDN1163 is a small molecule activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).

CDN1163, which markedly lowered fasting blood glucose, improved glucose tolerance, and ameliorated hepatosteatosis but did not alter glucose levels or body weight in lean controls.?Importantly, CDN1163-treated ob/ob mice maintained euglycemia comparable with that of lean mice for >6 weeks after cessation of CDN1163 administration[1].

892711-75-0

C20H20N2O2

320.392

DMSO:50 mg/mL (156.06 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years