Polymyxin B nonapeptide acetate(86408-36-8 free base) 是一种阳离子环肽。 Polyxin B九肽是polyxin B经酶解产生的衍生物。与polyxin B相比，polyxin B九肽毒性低，缺乏杀菌活性，仍具有破坏革兰氏阴性菌外膜的能力。

Polymyxin B nonapeptide acetate is a cationic cyclic peptide. Polyxin B nonapeptide is a derivative produced by enzymatic cleavage of polyxin B. Compared with polyxin B, polyxin B nonapeptide has low toxicity, lacks bactericidal activity and still has the ability to destroy the outer membrane of Gram-negative bacteria.

Polymyxin B nonapeptide Acetate, a cationic cyclic peptide derived by enzymatic processing from the naturally occurring peptide polymyxin B, is able to increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics probably by binding to the bacterial lipopolysaccharide (LPS)[1].

TP1341L

C45H78N14O13

1023.19

Polymyxin B nonapeptide acetate(86408-36-8 free base)

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years