Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.

Mcl1-IN-9 inhibits growth of Mcl-1 dependent tumor cell lines in the nanomolar range.

Mcl1-IN-9 inhibits the growth of?triple negative breast cancer xenografts and hematological at well tolerated doses.

1810769-31-3

C37H39ClN4O4

639.18

Mcl1-IN-9

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years