GSK172981 is a non-peptide tachykinin NK3 receptor antagonist with a high affinity for the recombinant human (PK (I) value 7.7) and native guinea pig (PK (I) value 7.8) tachykinin NK3 receptor. In vitro, the functional evaluation showed that GSK172981 was a competitive antagonist for the cloned human tachykinin NK(3) receptor (PA (2)=7.2). GSK172981 may be used to treat schizophrenia.

1133705-99-3

C26H22FN3O

411.47

GSK-172981;GSK 172981;GSK172981

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years